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Triptolide Inhibited Cytotoxicity of Differentiated PC12 Cells Induced by Amyloid-Beta(25–35) via the Autophagy Pathway

Evidence shows that an abnormal deposition of amyloid beta-peptide(25–35) (Aβ(25–35)) was the primary cause of the pathogenesis of Alzheimer’s disease (AD). And the elimination of Aβ(25–35) is considered an important target for the treatment of AD. Triptolide (TP), isolated from Tripterygium wilford...

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Detalles Bibliográficos
Autores principales:	Xu, Pengjuan, Li, Zhigui, Wang, Hui, Zhang, Xiaochen, Yang, Zhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640509/ https://www.ncbi.nlm.nih.gov/pubmed/26554937 http://dx.doi.org/10.1371/journal.pone.0142719

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