Type 1 Diabetes Prevention in NOD Mice by Targeting DPPIV/CD26 Is Associated with Changes in CD8(+)T Effector Memory Subset

CD26 is a T cell activation marker consisting in a type II transmembrane glycoprotein with dipeptidyl peptidase IV (DPPIV) activity in its extracellular domain. It has been described that DPPIV inhibition delays the onset of type 1 diabetes and reverses the disease in non-obese diabetic (NOD) mice....

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Detalles Bibliográficos
Autores principales: Alonso, Núria, Julián, María Teresa, Carrascal, Jorge, Colobran, Roger, Pujol-Autonell, Irma, Rodriguez-Fernández, Silvia, Teniente, Aina, Fernández, Marco Antonio, Miñarro, Antoni, Ruiz de Villa, María Carmen, Vives-Pi, Marta, Puig-Domingo, Manel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640511/
https://www.ncbi.nlm.nih.gov/pubmed/26555789
http://dx.doi.org/10.1371/journal.pone.0142186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640511/
https://www.ncbi.nlm.nih.gov/pubmed/26555789
http://dx.doi.org/10.1371/journal.pone.0142186

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