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Simple Genome Editing of Rodent Intact Embryos by Electroporation

The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system is a powerful tool for genome editing in animals. Recently, new technology has been developed to genetically modify animals without using highly skilled techniques, such as pronuclear microinjection...

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Detalles Bibliográficos
Autores principales: Kaneko, Takehito, Mashimo, Tomoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640526/
https://www.ncbi.nlm.nih.gov/pubmed/26556280
http://dx.doi.org/10.1371/journal.pone.0142755