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Simple Genome Editing of Rodent Intact Embryos by Electroporation
The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) system is a powerful tool for genome editing in animals. Recently, new technology has been developed to genetically modify animals without using highly skilled techniques, such as pronuclear microinjection...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640526/ https://www.ncbi.nlm.nih.gov/pubmed/26556280 http://dx.doi.org/10.1371/journal.pone.0142755 |