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Human CD180 Transmits Signals via the PIM-1L Kinase

Toll-like receptors (TLRs) are important sensors of the innate immune system that recognize conserved structural motifs and activate cells via a downstream signaling cascade. The CD180/MD1 molecular complex is an unusual member of the TLR family, since it lacks the components that are normally requi...

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Detalles Bibliográficos
Autores principales: Egli, Nicole, Zajonz, Alexandra, Burger, Matthew T., Schweighoffer, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640547/
https://www.ncbi.nlm.nih.gov/pubmed/26555723
http://dx.doi.org/10.1371/journal.pone.0142741