Mutational Profiling Can Establish Clonal or Independent Origin in Synchronous Bilateral Breast and Other Tumors

BACKGROUND: Synchronous tumors can be independent primary tumors or a primary-metastatic (clonal) pair, which may have clinical implications. Mutational profiling of tumor DNA is increasingly common in the clinic. We investigated whether mutational profiling can distinguish independent from clonal t...

Descripción completa

Detalles Bibliográficos
Autores principales: Bao, Lei, Messer, Karen, Schwab, Richard, Harismendy, Olivier, Pu, Minya, Crain, Brian, Yost, Shawn, Frazer, Kelly A., Rana, Brinda, Hasteh, Farnaz, Wallace, Anne, Parker, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640562/
https://www.ncbi.nlm.nih.gov/pubmed/26554380
http://dx.doi.org/10.1371/journal.pone.0142487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640562/
https://www.ncbi.nlm.nih.gov/pubmed/26554380
http://dx.doi.org/10.1371/journal.pone.0142487

Ejemplares similares