An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal States

Reversible epithelial-to-mesenchymal transition (EMT) is central to tissue development, epithelial stemness, and cancer metastasis. While many regulatory elements have been identified to induce EMT, the complex process underlying such cellular plasticity remains poorly understood. Utilizing a system...

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Detalles Bibliográficos
Autores principales: Hong, Tian, Watanabe, Kazuhide, Ta, Catherine Ha, Villarreal-Ponce, Alvaro, Nie, Qing, Dai, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640575/
https://www.ncbi.nlm.nih.gov/pubmed/26554584
http://dx.doi.org/10.1371/journal.pcbi.1004569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640575/
https://www.ncbi.nlm.nih.gov/pubmed/26554584
http://dx.doi.org/10.1371/journal.pcbi.1004569

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