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Isolation of bis(copper) key intermediates in Cu-catalyzed azide-alkyne “click reaction”

The copper-catalyzed 1,3-dipolar cycloaddition of an azide to a terminal alkyne (CuAAC) is one of the most popular chemical transformations, with applications ranging from material to life sciences. However, despite many mechanistic studies, direct observation of key components of the catalytic cycl...

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Detalles Bibliográficos
Autores principales: Jin, Liqun, Tolentino, Daniel R., Melaimi, Mohand, Bertrand, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640605/
https://www.ncbi.nlm.nih.gov/pubmed/26601202
http://dx.doi.org/10.1126/sciadv.1500304