Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics

Over the past 4 years, nearly 100 exome sequencing studies have revealed the high frequency of mutations in the genes encoding the subunits of ATP-dependent chromatin remodelers in human cancer. Most of these mutations are within the genes encoding subunits of the BAF (Brg/Brahma-associated factors)...

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Detalles Bibliográficos
Autores principales: Kadoch, Cigall, Crabtree, Gerald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640607/
https://www.ncbi.nlm.nih.gov/pubmed/26601204
http://dx.doi.org/10.1126/sciadv.1500447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640607/
https://www.ncbi.nlm.nih.gov/pubmed/26601204
http://dx.doi.org/10.1126/sciadv.1500447

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