Structure of the mycobacterial ATP synthase F(o) rotor ring in complex with the anti-TB drug bedaquiline
Multidrug-resistant tuberculosis (MDR-TB) is more prevalent today than at any other time in human history. Bedaquiline (BDQ), a novel Mycobacterium-specific adenosine triphosphate (ATP) synthase inhibitor, is the first drug in the last 40 years to be approved for the treatment of MDR-TB. This bacter...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640650/ https://www.ncbi.nlm.nih.gov/pubmed/26601184 http://dx.doi.org/10.1126/sciadv.1500106 |