Structure of the mycobacterial ATP synthase F(o) rotor ring in complex with the anti-TB drug bedaquiline

Multidrug-resistant tuberculosis (MDR-TB) is more prevalent today than at any other time in human history. Bedaquiline (BDQ), a novel Mycobacterium-specific adenosine triphosphate (ATP) synthase inhibitor, is the first drug in the last 40 years to be approved for the treatment of MDR-TB. This bacter...

Descripción completa

Detalles Bibliográficos
Autores principales: Preiss, Laura, Langer, Julian D., Yildiz, Özkan, Eckhardt-Strelau, Luise, Guillemont, Jérôme E. G., Koul, Anil, Meier, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640650/
https://www.ncbi.nlm.nih.gov/pubmed/26601184
http://dx.doi.org/10.1126/sciadv.1500106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640650/
https://www.ncbi.nlm.nih.gov/pubmed/26601184
http://dx.doi.org/10.1126/sciadv.1500106

Ejemplares similares