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Structure of the mycobacterial ATP synthase F(o) rotor ring in complex with the anti-TB drug bedaquiline

Multidrug-resistant tuberculosis (MDR-TB) is more prevalent today than at any other time in human history. Bedaquiline (BDQ), a novel Mycobacterium-specific adenosine triphosphate (ATP) synthase inhibitor, is the first drug in the last 40 years to be approved for the treatment of MDR-TB. This bacter...

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Detalles Bibliográficos
Autores principales:	Preiss, Laura, Langer, Julian D., Yildiz, Özkan, Eckhardt-Strelau, Luise, Guillemont, Jérôme E. G., Koul, Anil, Meier, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640650/ https://www.ncbi.nlm.nih.gov/pubmed/26601184 http://dx.doi.org/10.1126/sciadv.1500106

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