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NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions

Mutations of the PTEN-induced putative kinase 1 (PINK1) gene are a cause of autosomal recessive forms of Parkinson’s disease. Recent studies have revealed that PINK1 is an essential factor for controlling mitochondrial quality, and that it protects cells from oxidative stresses. Although there has b...

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Detalles Bibliográficos
Autores principales: Murata, Hitoshi, Takamatsu, Hitoshi, Liu, Sulai, Kataoka, Ken, Huh, Nam-ho, Sakaguchi, Masakiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640816/
https://www.ncbi.nlm.nih.gov/pubmed/26555609
http://dx.doi.org/10.1371/journal.pone.0142438