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NRF2 Regulates PINK1 Expression under Oxidative Stress Conditions
Mutations of the PTEN-induced putative kinase 1 (PINK1) gene are a cause of autosomal recessive forms of Parkinson’s disease. Recent studies have revealed that PINK1 is an essential factor for controlling mitochondrial quality, and that it protects cells from oxidative stresses. Although there has b...
Autores principales: | Murata, Hitoshi, Takamatsu, Hitoshi, Liu, Sulai, Kataoka, Ken, Huh, Nam-ho, Sakaguchi, Masakiyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640816/ https://www.ncbi.nlm.nih.gov/pubmed/26555609 http://dx.doi.org/10.1371/journal.pone.0142438 |
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