Whole Exome Sequencing of Rapid Autopsy Tumors and Xenograft Models Reveals Possible Driver Mutations Underlying Tumor Progression

Pancreatic Ductal Adenocarcinoma (PDAC) is a highly lethal malignancy due to its propensity to invade and rapidly metastasize and remains very difficult to manage clinically. One major hindrance towards a better understanding of PDAC is the lack of molecular data sets and models representative of en...

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Detalles Bibliográficos
Autores principales: Xie, Tao, Musteanu, Monica, Lopez-Casas, Pedro P., Shields, David J., Olson, Peter, Rejto, Paul A., Hidalgo, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640827/
https://www.ncbi.nlm.nih.gov/pubmed/26555578
http://dx.doi.org/10.1371/journal.pone.0142631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640827/
https://www.ncbi.nlm.nih.gov/pubmed/26555578
http://dx.doi.org/10.1371/journal.pone.0142631

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