The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress

Neuropilin-1 (NRP-1) is a transmembrane glycoprotein. As a VEGF co-receptor, NRP1 significantly enhances VEGFR2 signaling and promotes vascular permeability and migration. The purpose of this study was to evaluate the effects of an NRP-1 inhibitor, ATWLPPR peptide, on the early stages of diabetic re...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Wang, Shuaiwei, Li, Mengling, Wu, Dongdong, Liu, Fang, Yang, Ruisheng, Ji, Shaoping, Ji, Ailing, Li, Yanzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640834/
https://www.ncbi.nlm.nih.gov/pubmed/26554379
http://dx.doi.org/10.1371/journal.pone.0142571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640834/
https://www.ncbi.nlm.nih.gov/pubmed/26554379
http://dx.doi.org/10.1371/journal.pone.0142571

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