A Naturally Occurring rev1-vpu Fusion Gene Does Not Confer a Fitness Advantage to HIV-1

BACKGROUND: Pandemic strains of HIV-1 (group M) encode a total of nine structural (gag, pol, env), regulatory (rev, tat) and accessory (vif, vpr, vpu, nef) genes. However, some subtype A and C viruses exhibit an unusual gene arrangement in which the first exon of rev (rev1) and the vpu gene are plac...

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Detalles Bibliográficos
Autores principales: Langer, Simon M., Hopfensperger, Kristina, Iyer, Shilpa S., Kreider, Edward F., Learn, Gerald H., Lee, Lan-Hui, Hahn, Beatrice H., Sauter, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640844/
https://www.ncbi.nlm.nih.gov/pubmed/26554585
http://dx.doi.org/10.1371/journal.pone.0142118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640844/
https://www.ncbi.nlm.nih.gov/pubmed/26554585
http://dx.doi.org/10.1371/journal.pone.0142118

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