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A Naturally Occurring rev1-vpu Fusion Gene Does Not Confer a Fitness Advantage to HIV-1
BACKGROUND: Pandemic strains of HIV-1 (group M) encode a total of nine structural (gag, pol, env), regulatory (rev, tat) and accessory (vif, vpr, vpu, nef) genes. However, some subtype A and C viruses exhibit an unusual gene arrangement in which the first exon of rev (rev1) and the vpu gene are plac...
Autores principales: | Langer, Simon M., Hopfensperger, Kristina, Iyer, Shilpa S., Kreider, Edward F., Learn, Gerald H., Lee, Lan-Hui, Hahn, Beatrice H., Sauter, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640844/ https://www.ncbi.nlm.nih.gov/pubmed/26554585 http://dx.doi.org/10.1371/journal.pone.0142118 |
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