A Novel Adeno-Associated Virus–Based Genetic Vaccine Encoding the Hepatitis C Virus NS3/4 Protein Exhibits Immunogenic Properties in Mice Superior to Those of an NS3-Protein-Based Vaccine

More than 170 million individuals worldwide are infected with hepatitis C virus (HCV), and up to an estimated 30% of chronically infected individuals will go on to develop progressive liver disease. Despite the recent advances in antiviral treatment of HCV infection, it remains a major public health...

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Detalles Bibliográficos
Autores principales: Zhu, Fengqin, Chen, Tian, Zhang, Yeqiong, Sun, Haixia, Cao, Hong, Lu, Jianxi, Zhao, Linshan, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640878/
https://www.ncbi.nlm.nih.gov/pubmed/26556235
http://dx.doi.org/10.1371/journal.pone.0142349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640878/
https://www.ncbi.nlm.nih.gov/pubmed/26556235
http://dx.doi.org/10.1371/journal.pone.0142349

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