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TAK-242, a Toll-Like Receptor 4 Antagonist, Protects against Aldosterone-Induced Cardiac and Renal Injury

Cardiovascular and renal inflammation induced by Aldosterone (Aldo) plays an important role in the pathogenesis of hypertension and renal fibrosis. Toll-like receptor 4 (TLR4) signaling contributes to inflammatory cardiovascular and renal diseases, but its role in Aldo-induced hypertension and renal...

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Detalles Bibliográficos
Autores principales: Zhang, Yide, Peng, Weisheng, Ao, Xiang, Dai, Houyong, Yuan, Li, Huang, Xinzhong, Zhou, Qiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640881/
https://www.ncbi.nlm.nih.gov/pubmed/26556241
http://dx.doi.org/10.1371/journal.pone.0142456