Conditional PDK1 ablation promotes epidermal and T cell-mediated dysfunctions leading to inflammatory skin disease

Phosphoinositide dependent kinase-1 (PDK1) is a key signaling molecule downstream of the phosphatidylinositol 3-kinase (PI-3 kinase) pathway and is a master regulator of multiple kinases in cells of epithelial and hematopoietic lineages. The physiological role of PDK1 in regulating skin and immune h...

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Detalles Bibliográficos
Autores principales: Yu, Minjun, Owens, David M., Ghosh, Sankar, Farber, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640961/
https://www.ncbi.nlm.nih.gov/pubmed/26099023
http://dx.doi.org/10.1038/jid.2015.232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640961/
https://www.ncbi.nlm.nih.gov/pubmed/26099023
http://dx.doi.org/10.1038/jid.2015.232

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