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Cell Surface CD74-MIF Interactions Drive Melanoma Survival in Response to Interferon-γ

While melanoma is believed to be a highly immunogenic tumor and recent developments in immunotherapies are promising. Interferon-γ (IFN-γ) produced by immune cells plays a crucial role in tumor immune surveillance; however, it has also been reported to be pro-tumorigenic. In the current study, we fo...

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Detalles Bibliográficos
Autores principales: Tanese, Keiji, Hashimoto, Yuuri, Berkova, Zuzana, Wang, Yuling, Samaniego, Felipe, Lee, Jeffrey E., Ekmekcioglu, Suhendan, Grimm, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640965/
https://www.ncbi.nlm.nih.gov/pubmed/26039541
http://dx.doi.org/10.1038/jid.2015.204