Altered regulation of PDK4 expression promotes antiestrogen resistance in human breast cancer cells

Acquired or de novo resistance to the selective estrogen receptor modulators tamoxifen and fulvestrant (ICI) is a major barrier to successful treatment of breast cancer. Gene expression patterns in tamoxifen resistant (TamR-MCF-7) cells were compared to their parental cells (MCF-7L) to identify an a...

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Detalles Bibliográficos
Autores principales: Walter, William, Thomalla, Jennifer, Bruhn, Josh, Fagan, Dedra H., Zehowski, Cheryl, Yee, Douglas, Skildum, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641142/
https://www.ncbi.nlm.nih.gov/pubmed/26576332
http://dx.doi.org/10.1186/s40064-015-1444-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641142/
https://www.ncbi.nlm.nih.gov/pubmed/26576332
http://dx.doi.org/10.1186/s40064-015-1444-2

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