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Association between Serum Soluble Klotho Levels and Mortality in Chronic Hemodialysis Patients

Klotho is a single-pass transmembrane protein predominantly expressed in the kidney. The extracellular domain of Klotho is subject to ectodomain shedding and is released into the circulation as a soluble form. Soluble Klotho is also generated from alternative splicing of the Klotho gene. In mice, de...

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Detalles Bibliográficos
Autores principales: Otani-Takei, Naoko, Masuda, Takahiro, Akimoto, Tetsu, Honma, Sumiko, Watanabe, Yuko, Shiizaki, Kazuhiro, Miki, Takuya, Kusano, Eiji, Asano, Yasushi, Kuro-o, Makoto, Nagata, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641198/
https://www.ncbi.nlm.nih.gov/pubmed/26604925
http://dx.doi.org/10.1155/2015/406269