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Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9
BACKGROUND: Gene therapy strategies are promising therapeutic options for monogenic muscular dystrophies, with several currently underways. The adeno-associated viral (AAV) vector is among the most effective gene delivery systems. However, transduction efficiency in skeletal muscles varies between A...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641337/ https://www.ncbi.nlm.nih.gov/pubmed/26561520 http://dx.doi.org/10.1186/s13395-015-0064-4 |