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Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9

BACKGROUND: Gene therapy strategies are promising therapeutic options for monogenic muscular dystrophies, with several currently underways. The adeno-associated viral (AAV) vector is among the most effective gene delivery systems. However, transduction efficiency in skeletal muscles varies between A...

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Detalles Bibliográficos
Autores principales: Riaz, Muhammad, Raz, Yotam, Moloney, Elizabeth B., van Putten, Maaike, Krom, Yvonne D., van der Maarel, Silvere M., Verhaagen, Joost, Raz, Vered
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641337/
https://www.ncbi.nlm.nih.gov/pubmed/26561520
http://dx.doi.org/10.1186/s13395-015-0064-4