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SUMOylation of sPRDM16 promotes the progression of acute myeloid leukemia
BACKGROUND: In addition to genetic and epigenetic alteration, post-translational modification of proteins plays a critical role in the initiation, progression and maturation of acute myeloid leukemia (AML). METHODS: The SUMOylation site of sPRDM16 at K568 was mutated to arginine by site-directed mut...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641379/ https://www.ncbi.nlm.nih.gov/pubmed/26559765 http://dx.doi.org/10.1186/s12885-015-1844-2 |