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SUMOylation of sPRDM16 promotes the progression of acute myeloid leukemia

BACKGROUND: In addition to genetic and epigenetic alteration, post-translational modification of proteins plays a critical role in the initiation, progression and maturation of acute myeloid leukemia (AML). METHODS: The SUMOylation site of sPRDM16 at K568 was mutated to arginine by site-directed mut...

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Detalles Bibliográficos
Autores principales:	Dong, Song, Chen, Jieping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641379/ https://www.ncbi.nlm.nih.gov/pubmed/26559765 http://dx.doi.org/10.1186/s12885-015-1844-2

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