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Two alternative pathways for generating transmissible prion disease de novo

INTRODUCTION: Previous studies established that prion disease with unique strain-specific phenotypes could be induced by in vitro-formed recombinant PrP (rPrP) fibrils with structures different from that of authentic prions, or PrP(Sc). To explain the etiology of prion diseases, new mechanism propos...

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Detalles Bibliográficos
Autores principales:	Makarava, Natallia, Savtchenko, Regina, Baskakov, Ilia V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641408/ https://www.ncbi.nlm.nih.gov/pubmed/26556038 http://dx.doi.org/10.1186/s40478-015-0248-5

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