Impact of Charged Particle Exposure on Homologous DNA Double-Strand Break Repair in Human Blood-Derived Cells

Ionizing radiation generates DNA double-strand breaks (DSB) which, unless faithfully repaired, can generate chromosomal rearrangements in hematopoietic stem and/or progenitor cells (HSPC), potentially priming the cells towards a leukemic phenotype. Using an enhanced green fluorescent protein (EGFP)-...

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Detalles Bibliográficos
Autores principales: Rall, Melanie, Kraft, Daniela, Volcic, Meta, Cucu, Aljona, Nasonova, Elena, Taucher-Scholz, Gisela, Bönig, Halvard, Wiesmüller, Lisa, Fournier, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641431/
https://www.ncbi.nlm.nih.gov/pubmed/26618143
http://dx.doi.org/10.3389/fonc.2015.00250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641431/
https://www.ncbi.nlm.nih.gov/pubmed/26618143
http://dx.doi.org/10.3389/fonc.2015.00250

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