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Treatment of Clostridium difficile infection in mice with vancomycin alone is as effective as treatment with vancomycin and metronidazole in combination

OBJECTIVE: Clostridium difficile is a major cause of nosocomial infectious diarrhoea. Treatment of C. difficile infection (CDI) depends on disease severity. A combination of vancomycin and metronidazole is often recommended in severe cases. The aim of this study was to examine, in a murine model of...

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Detalles Bibliográficos
Autores principales: Erikstrup, Lise Tornvig, Aarup, Mie, Hagemann-Madsen, Rikke, Dagnaes-Hansen, Frederik, Kristensen, Brian, Olsen, Katharina Elisabeth Pribil, Fuursted, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641438/
https://www.ncbi.nlm.nih.gov/pubmed/26568840
http://dx.doi.org/10.1136/bmjgast-2015-000038