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Amination of ω-Functionalized Aliphatic Primary Alcohols by a Biocatalytic Oxidation–Transamination Cascade

Amination of non-activated aliphatic fatty alcohols to the corresponding primary amines was achieved through a five-enzyme cascade reaction by coupling a long-chain alcohol oxidase from Aspergillus fumigatus (LCAO_Af) with a ω-transaminase from Chromobacterium violaceum (ω-TA_Cv). The alcohol was ox...

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Detalles Bibliográficos
Autores principales: Pickl, Mathias, Fuchs, Michael, Glueck, Silvia M, Faber, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641459/
https://www.ncbi.nlm.nih.gov/pubmed/26583050
http://dx.doi.org/10.1002/cctc.201500589