Cargando…

A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates

By replacing the central thiophene unit of an anionic pentameric oligothiophene with other heterocyclic moities, a palette of pentameric thiophene-based ligands with distinct fluorescent properties were synthesized. All ligands displayed superior selectivity towards recombinant amyloid fibrils as we...

Descripción completa

Detalles Bibliográficos
Autores principales: Shirani, Hamid, Linares, Mathieu, Sigurdson, Christina J, Lindgren, Mikael, Norman, Patrick, Nilsson, K Peter R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641461/
https://www.ncbi.nlm.nih.gov/pubmed/26388448
http://dx.doi.org/10.1002/chem.201502999