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Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions
Acetylation is frequently detected on mitochondrial enzymes, and the sirtuin deacetylase SIRT3 is thought to regulate metabolism by deacetylating mitochondrial proteins. However, the stoichiometry of acetylation has not been studied and is important for understanding whether SIRT3 regulates or suppr...
Autores principales: | Weinert, Brian T, Moustafa, Tarek, Iesmantavicius, Vytautas, Zechner, Rudolf, Choudhary, Chunaram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641529/ https://www.ncbi.nlm.nih.gov/pubmed/26358839 http://dx.doi.org/10.15252/embj.201591271 |
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