Disruption of Fractalkine Signaling Leads to Microglial Activation and Neuronal Damage in the Diabetic Retina

Fractalkine (CX3CL1 or FKN) is a membrane-bound chemokine expressed on neuronal membranes and is proteolytically cleaved to shed a soluble chemoattractant domain. FKN signals via its unique receptor CX3CR1 expressed on microglia and other peripheral leukocytes. The aim of this study is to determine...

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Detalles Bibliográficos
Autores principales: Cardona, Sandra M., Mendiola, Andrew S., Yang, Ya-Chin, Adkins, Sarina L., Torres, Vanessa, Cardona, Astrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641555/
https://www.ncbi.nlm.nih.gov/pubmed/26514658
http://dx.doi.org/10.1177/1759091415608204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641555/
https://www.ncbi.nlm.nih.gov/pubmed/26514658
http://dx.doi.org/10.1177/1759091415608204

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