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Spaceflight Effects on Cytochrome P450 Content in Mouse Liver

Hard conditions of long-term manned spaceflight can affect functions of many biological systems including a system of drug metabolism. The cytochrome P450 (CYP) superfamily plays a key role in the drug metabolism. In this study we examined the hepatic content of some P450 isoforms in mice exposed to...

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Detalles Bibliográficos
Autores principales: Moskaleva, Natalia, Moysa, Alexander, Novikova, Svetlana, Tikhonova, Olga, Zgoda, Victor, Archakov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641588/
https://www.ncbi.nlm.nih.gov/pubmed/26561010
http://dx.doi.org/10.1371/journal.pone.0142374