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Absolute Quantification of Endogenous Ras Isoform Abundance

Ras proteins are important signalling hubs situated near the top of networks controlling cell proliferation, differentiation and survival. Three almost identical isoforms, HRAS, KRAS and NRAS, are ubiquitously expressed yet have differing biological and oncogenic properties. In order to help underst...

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Detalles Bibliográficos
Autores principales: Mageean, Craig J., Griffiths, John R., Smith, Duncan L., Clague, Michael J., Prior, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641634/
https://www.ncbi.nlm.nih.gov/pubmed/26560143
http://dx.doi.org/10.1371/journal.pone.0142674