Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells

Statins are widely used in the treatment of hypercholesterolemia and are efficient in the prevention of cardiovascular disease. Molecular mechanisms explaining statin-induced impairment in insulin secretion remain largely unknown. In the current study, we show that simvastatin decreased glucose-stim...

Descripción completa

Detalles Bibliográficos
Autores principales: Yaluri, Nagendra, Modi, Shalem, López Rodríguez, Maykel, Stančáková, Alena, Kuusisto, Johanna, Kokkola, Tarja, Laakso, Markku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641640/
https://www.ncbi.nlm.nih.gov/pubmed/26561346
http://dx.doi.org/10.1371/journal.pone.0142902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641640/
https://www.ncbi.nlm.nih.gov/pubmed/26561346
http://dx.doi.org/10.1371/journal.pone.0142902

Ejemplares similares