Characterizing Protease Specificity: How Many Substrates Do We Need?

Calculation of cleavage entropies allows to quantify, map and compare protease substrate specificity by an information entropy based approach. The metric intrinsically depends on the number of experimentally determined substrates (data points). Thus a statistical analysis of its numerical stability...

Descripción completa

Detalles Bibliográficos
Autores principales: Schauperl, Michael, Fuchs, Julian E., Waldner, Birgit J., Huber, Roland G., Kramer, Christian, Liedl, Klaus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641643/
https://www.ncbi.nlm.nih.gov/pubmed/26559682
http://dx.doi.org/10.1371/journal.pone.0142658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641643/
https://www.ncbi.nlm.nih.gov/pubmed/26559682
http://dx.doi.org/10.1371/journal.pone.0142658

Ejemplares similares