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Immunogenicity and Protective Efficacy of Brugia malayi Heavy Chain Myosin as Homologous DNA, Protein and Heterologous DNA/Protein Prime Boost Vaccine in Rodent Model

We earlier demonstrated the immunoprophylactic efficacy of recombinant heavy chain myosin (Bm-Myo) of Brugia malayi (B. malayi) in rodent models. In the current study, further attempts have been made to improve this efficacy by employing alternate approaches such as homologous DNA (pcD-Myo) and hete...

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Detalles Bibliográficos
Autores principales: Gupta, Jyoti, Pathak, Manisha, Misra, Sweta, Misra-Bhattacharya, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641661/
https://www.ncbi.nlm.nih.gov/pubmed/26560102
http://dx.doi.org/10.1371/journal.pone.0142548