Tackling Glaucoma from within the Brain: An Unfortunate Interplay of BDNF and TrkB

According to the neurotrophin deprivation hypothesis, diminished retrograde delivery of neurotrophic support during an early stage of glaucoma pathogenesis is one of the main triggers that induce retinal ganglion cell (RGC) degeneration. Therefore, interfering with neurotrophic signaling seems an at...

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Detalles Bibliográficos
Autores principales: Dekeyster, Eline, Geeraerts, Emiel, Buyens, Tom, Van den Haute, Chris, Baekelandt, Veerle, De Groef, Lies, Salinas-Navarro, Manuel, Moons, Lieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641732/
https://www.ncbi.nlm.nih.gov/pubmed/26560713
http://dx.doi.org/10.1371/journal.pone.0142067