Alpha-synuclein Toxicity in the Early Secretory Pathway: How It Drives Neurodegeneration in Parkinsons Disease

Alpha-synuclein is a predominant player in the pathogenesis of Parkinson's Disease. However, despite extensive study for two decades, its physiological and pathological mechanisms remain poorly understood. Alpha-synuclein forms a perplexing web of interactions with lipids, trafficking machinery...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Hay, Jesse C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641903/
https://www.ncbi.nlm.nih.gov/pubmed/26617485
http://dx.doi.org/10.3389/fnins.2015.00433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641903/
https://www.ncbi.nlm.nih.gov/pubmed/26617485
http://dx.doi.org/10.3389/fnins.2015.00433

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