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Global Identification of Protein Post-translational Modifications in a Single-Pass Database Search

[Image: see text] Bottom-up proteomics database search algorithms used for peptide identification cannot comprehensively identify post-translational modifications (PTMs) in a single-pass because of high false discovery rates (FDRs). A new approach to database searching enables global PTM (G-PTM) ide...

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Detalles Bibliográficos
Autores principales: Shortreed, Michael R., Wenger, Craig D., Frey, Brian L., Sheynkman, Gloria M., Scalf, Mark, Keller, Mark P., Attie, Alan D., Smith, Lloyd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642219/
https://www.ncbi.nlm.nih.gov/pubmed/26418581
http://dx.doi.org/10.1021/acs.jproteome.5b00599