Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection

Tal-effector nucleases (TALEN) and clustered regularly interspaced short palindromic repeats (CRISPR) with CRISPR-associated (Cas) proteins are genome editing tools with unprecedented potential. However, the ability to deliver optimal amounts of these nucleases into mammalian cells with minimal toxi...

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Detalles Bibliográficos
Autores principales: Cottle, Renee N., Lee, Ciaran M., Archer, David, Bao, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642230/
https://www.ncbi.nlm.nih.gov/pubmed/26558999
http://dx.doi.org/10.1038/srep16031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642230/
https://www.ncbi.nlm.nih.gov/pubmed/26558999
http://dx.doi.org/10.1038/srep16031

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