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Pulsed Azidohomoalanine Labeling in Mammals (PALM) Detects Changes in Liver-Specific LKB1 Knockout Mice

[Image: see text] Quantification of proteomes by mass spectrometry has proven to be useful to study human pathology recapitulated in cellular or animal models of disease. Enriching and quantifying newly synthesized proteins (NSPs) at set time points by mass spectrometry has the potential to identify...

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Detalles Bibliográficos
Autores principales: McClatchy, Daniel B., Ma, Yuanhui, Liu, Chao, Stein, Benjamin D., Martínez-Bartolomé, Salvador, Vasquez, Debbie, Hellberg, Kristina, Shaw, Reuben J., Yates, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642245/
https://www.ncbi.nlm.nih.gov/pubmed/26445171
http://dx.doi.org/10.1021/acs.jproteome.5b00653