Cofilin 1 activation prevents the defects in axon elongation and guidance induced by extracellular alpha-synuclein

Impaired adult neurogenesis and axon traumatic injury participate in the severity of neurodegenerative diseases. Alpha-synuclein, a cytosolic protein involved in Parkinson’s disease, may be released from neurons, suggesting a role for excess secreted alpha-synuclein in the onset and spread of the pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Tilve, Sharada, Difato, Francesco, Chieregatti, Evelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642265/
https://www.ncbi.nlm.nih.gov/pubmed/26558842
http://dx.doi.org/10.1038/srep16524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642265/
https://www.ncbi.nlm.nih.gov/pubmed/26558842
http://dx.doi.org/10.1038/srep16524

Ejemplares similares