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Cofilin 1 activation prevents the defects in axon elongation and guidance induced by extracellular alpha-synuclein
Impaired adult neurogenesis and axon traumatic injury participate in the severity of neurodegenerative diseases. Alpha-synuclein, a cytosolic protein involved in Parkinson’s disease, may be released from neurons, suggesting a role for excess secreted alpha-synuclein in the onset and spread of the pa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642265/ https://www.ncbi.nlm.nih.gov/pubmed/26558842 http://dx.doi.org/10.1038/srep16524 |