Mechanosensitive TRPM7 mediates shear stress and modulates osteogenic differentiation of mesenchymal stromal cells through Osterix pathway

Microenvironments that modulate fate commitments of mesenchymal stromal cells (MSCs) are composed of chemical and physical cues, but the latter ones are much less investigated. Here we demonstrate that intermittent fluid shear stress (IFSS), a potent and physiologically relevant mechanical stimulus,...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Shiuan, Liu, Yu-An, Huang, Chin-Jing, Yen, Meng-Hua, Tseng, Chien-Tzu, Chien, Shu, Lee, Oscar K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642269/
https://www.ncbi.nlm.nih.gov/pubmed/26558702
http://dx.doi.org/10.1038/srep16522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642269/
https://www.ncbi.nlm.nih.gov/pubmed/26558702
http://dx.doi.org/10.1038/srep16522

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