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Improvement in Mouse iPSC Induction by Rab32 Reveals the Importance of Lipid Metabolism during Reprogramming

Induced pluripotent stem cells (iPSCs) have variable expression levels of a series of genes that affect their pluripotent potential, but the regulatory mechanisms controlling reprogramming remain unclear. By testing the efficiency of iPSC generation using Oct4, Sox2, Klf4 (termed OSK) plus one addit...

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Detalles Bibliográficos
Autores principales: Pei, Yangli, Yue, Liang, Zhang, Wei, Wang, Yanliang, Wen, Bingqiang, Zhong, Liang, Xiang, Jinzhu, Li, Junhong, Zhang, Shaopeng, Wang, Hanning, Mu, Haiyuan, Wei, Qingqing, Han, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642270/
https://www.ncbi.nlm.nih.gov/pubmed/26559473
http://dx.doi.org/10.1038/srep16539