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NPM1 histone chaperone is upregulated in glioblastoma to promote cell survival and maintain nucleolar shape

Glioblastoma (grade IV glioma) is the most common and aggressive adult brain tumor. A better understanding of the biology of glioblastoma cells is crucial to identify molecular targets stimulating cell death. NPM1 (nucleophosmin) is a multifunctional chaperone that plays an important role in cancer...

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Detalles Bibliográficos
Autores principales: Holmberg Olausson, Karl, Elsir, Tamador, Moazemi Goudarzi, Kaveh, Nistér, Monica, Lindström, Mikael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642306/
https://www.ncbi.nlm.nih.gov/pubmed/26559910
http://dx.doi.org/10.1038/srep16495