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Chronic fetal exposure to caffeine altered resistance vessel functions via RyRs-BK(Ca) down-regulation in rat offspring

Caffeine modifies vascular/cardiac contractility. Embryonic exposure to caffeine altered cardiac functions in offspring. This study determined chronic influence of prenatal caffeine on vessel functions in offspring. Pregnant Sprague-Dawley rats (5-month-old) were exposed to high dose of caffeine, th...

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Detalles Bibliográficos
Autores principales: Li, Na, Li, Yongmei, Gao, Qinqin, Li, Dawei, Tang, Jiaqi, Sun, Miao, Zhang, Pengjie, Liu, Bailin, Mao, Caiping, Xu, Zhice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642531/
https://www.ncbi.nlm.nih.gov/pubmed/26277840
http://dx.doi.org/10.1038/srep13225