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Histamine deficiency exacerbates myocardial injury in acute myocardial infarction through impaired macrophage infiltration and increased cardiomyocyte apoptosis

Histamine is a biogenic amine that is widely distributed and has multiple functions, but the role it plays in acute myocardial infarction (AMI) remains unclear. In this study, we investigated the origin and contribution of endogenous histamine to AMI. Histidine decarboxylase (HDC) is the unique enzy...

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Detalles Bibliográficos
Autores principales: Deng, Long, Hong, Tao, Lin, Jinyi, Ding, Suling, Huang, Zheyong, Chen, Jinmiao, Jia, Jianguo, Zou, Yunzeng, Wang, Timothy C., Yang, Xiangdong, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642534/
https://www.ncbi.nlm.nih.gov/pubmed/26278136
http://dx.doi.org/10.1038/srep13131